我目前的研究领域可以称为人类数量遗传学(quantitative genetics。我们的研究往往需要大样本数据做支撑,成千、上万、甚至更多的参与者。目前该领域,大部分的可获得数据是欧洲人种的数据

所以,我写这个博客,关注一下目前我知道的收集中国人数据的队列研究(cohort study)。需要注意,中国有法律管控相关的队列研究,并且之前发生过争议事件

  • ChinaMap with 10k individuals: paper
  • WeGene with 0.1m individuals: paper
  • China Kadoorie Biobank with 0.5m individuals: paper, website
  • Taizhou longitudinal study with 0.2m individuals: news
  • Chinese National Twin Registry with 61k twin pairs: paper
  • Westlake BioBank for Chinese (WBBC): paper1, paper2, website
  • 中国队列共享平台
  • Guangxi, China: the Fangchenggang Area Male Health and Examination Survey (FAMHES) with 4,303 men paper1
  • 4D-SZ
  • gut microbiome and blood metabolites from BGI-Shenzhen, “3,432 Chinese individuals with whole-genome, whole-metagenome, anthropometric and blood metabolic trait data” - Liu et al. Nature Genetics 2022
  • COVID gwas from Wang Chaolong group at Wuhan, “genotyped 1457 (598/859 with severe/mild symptoms) and sequenced 1141 (severe/mild: 474/667) patients of Chinese ancestry” - Wu et al. Communications biology, 2021
  • fingerprint gwas from Jin Li group at Fudan/Shanghai, “9,909 individuals from three Han Chinese cohorts” - Li et al. Cell, 2022
  • NyuWa Chinese Population Variant Database (NCVD): paper, website
  • Chinese Millionome Database: paper, website
  • China Kadoorie Biobank

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